UACR + eGFR TESTING
eGFR TESTING ALONE MAY MISS EARLY SIGNS OF KIDNEY DAMAGE15
Even patients with normal eGFR are at increased risk of CKD progression if UACR levels are increased8
UACR is a more sensitive measure of early kidney damage, while eGFR is a more reliable indicator of later-stage loss of kidney function15,16
The Diabetes Canada Guidelines encourage physicians to test both eGFR and UACR at least once a year in patients with type 2 diabetes5
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CKD: chronic kidney disease; EASD: European Association for the Study of Diabetes; eGFR: estimated glomerular filtration rate; GFR: glomerular filtration rate; KDIGO: Kidney Disease Improving Global Outcomes; T2D: type 2 diabetes; UACR: urine albumin-to-creatinine ratio.
|5.||International Diabetes Federation. IDF Diabetes Atlas. 9th ed. Brussels; 2019. Accessed January 29, 2021. Available at: https://www.diabetesatlas.org.|
|8.||Levin A, Stevens PE, Bilous RW, et al. (2013). Kidney disease: Improving global outcomes (KDIGO) CKD work group. KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease. Kidney International Supplements, 3(1), 1-150. https://doi.org/10.1038/kisup.2012.73|
|15.||Campion CG, et al. Can J Kidney Health Dis. 2017;4:2054358117705371.|
|16.||Van der Velde M, et al. Kidney Int. 2011;79(12):1341–1352|
|17.||Cosentino F, et al.; ESC Scientific Document Group Eur Heart J. 2020;41(2):255–323.|